That can be a hard question to answer. You have to really know yourself sometimes to realize when a change is needed. For myself, when whatever I'm doing no longer is "fun" or "satisfying", it's time to start looking at doing other things. Obviously, some things can't be helped immediately, like employment, but starting yourself in the right direction is a good step to take, like shopping for other jobs, going back to school, getting other certifications, etc. In any case, it takes some deep thought to see what's wrong, and what can be done to help things. Take some time for yourself and meditate on it, then see what comes to mind.